Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | CETP | P11597 | 1/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9548086 | 0.85 | KMT2A (1.00) | KMT2ACETPPTGS2ALDH1A1HTT | |
| SCHEMBL3088398 | 0.84 | KMT2A (0.74) | KMT2ACETPPTGS2ALDH1A1HTT | |
| SCHEMBL8056967 | 0.83 | AR (0.72) | CETPPTGS2ARALDH1A1HTT | |
| SCHEMBL1304150 | 0.80 | CETP (1.00) | KMT2ACETPARCA12CA2 | |
| SCHEMBL9548091 | 0.76 | ALDH1A1 (0.77) | KMT2APTGS2ALDH1A1GAAHPGD | |
| SCHEMBL3102512 | 0.76 | KMT2A (0.65) | KMT2ACETPPTGS2CA12CA2 | |
| SCHEMBL18674648 | 0.76 | RAB9A (0.74) | KMT2AARALDH1A1HTTGAA | |
| SCHEMBL3100957 | 0.75 | KMT2A (0.64) | KMT2APTGS2ALDH1A1HTTGAA | |
| SCHEMBL9548077 | 0.74 | PTGS2 (0.67) | KMT2APTGS2ALDH1A1HTTGAA | |
| SCHEMBL11751124 | 0.74 | TSHR (0.68) | KMT2ACETPALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217971-A | Anticoagulants, hypotensive agents, antiallergens and antiinflammatory agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0377457-A1 | Thiazole compounds, processes for the preparation thereof, and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-11 | — | — | EP | disclosed |