Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230424 | 0.89 | ALDH1A1 (0.49) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL5227914 | 0.88 | CDK1 (0.53) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL5231082 | 0.86 | ALDH1A1 (0.43) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL5237280 | 0.86 | CES1 (0.49) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL5232901 | 0.85 | MAPK1 (0.46) | KMT2AMAPTALDH1A1TDP1LMNA | |
| SCHEMBL5228023 | 0.85 | CA2 (0.49) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL5234203 | 0.84 | ALDH1A1 (0.42) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL5227591 | 0.84 | CDK1 (0.52) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL5228196 | 0.83 | CA12 (0.49) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL5227872 | 0.82 | CYP19A1 (0.46) | MEN1KMT2AMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519932-B1 | BISARYLSULFONAMIDE COMPOUNDS AND THEIR USE IN CANCER THERAPY | CYCLACEL LTD (GB) | 2007-10-03 | — | — | EP | claimed |