Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5237280 | 0.90 | CES1 (0.49) | MEN1KMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL5231082 | 0.88 | ALDH1A1 (0.43) | CA2CA1MEN1KMT2ATDP1 | |
| SCHEMBL5234203 | 0.88 | ALDH1A1 (0.42) | CA2CA1MEN1KMT2ATDP1 | |
| SCHEMBL5227591 | 0.88 | CDK1 (0.52) | MEN1KMT2ATDP1ALDH1A1POLB | |
| SCHEMBL5228196 | 0.88 | CA12 (0.49) | CA2CA12CA9MEN1KMT2A | |
| SCHEMBL5227161 | 0.85 | MEN1 (0.48) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL5227928 | 0.85 | MEN1 (0.50) | CA2CA1MEN1KMT2ATDP1 | |
| SCHEMBL5233848 | 0.83 | ACLY (0.39) | CA2CA1MEN1KMT2AALDH1A1 | |
| SCHEMBL8342602 | 0.82 | DNMT1 (0.44) | CA2CA1CA12CA9MEN1 | |
| SCHEMBL5232126 | 0.81 | EPAS1 (0.40) | CA2CA1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519932-B1 | BISARYLSULFONAMIDE COMPOUNDS AND THEIR USE IN CANCER THERAPY | CYCLACEL LTD (GB) | 2007-10-03 | — | — | EP | claimed |