Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.53 |
| ▸ | CDK7 | P50613 | 2/20 | 0.53 |
| ▸ | CCNH | P51946 | 2/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230424 | 0.89 | ALDH1A1 (0.49) | CDK1CCNB1CCNA2CDK2CDK7 | |
| SCHEMBL5227928 | 0.88 | MEN1 (0.50) | FFAR4MAPTHTTALDH1A1HPGD | |
| SCHEMBL5228196 | 0.84 | CA12 (0.49) | FFAR4MAPTHTTALDH1A1TDP1 | |
| SCHEMBL5232901 | 0.81 | MAPK1 (0.46) | MAPTALDH1A1HPGDTDP1LMNA | |
| SCHEMBL7997885 | 0.81 | L3MBTL1 (0.40) | FFAR4MAPTHTTALDH1A1TDP1 | |
| SCHEMBL5231082 | 0.79 | ALDH1A1 (0.43) | MAPTHTTALDH1A1HPGDTDP1 | |
| SCHEMBL5237280 | 0.79 | CES1 (0.49) | MAPTALDH1A1TDP1LMNAMAPK1 | |
| SCHEMBL27176648 | 0.78 | L3MBTL1 (0.61) | CDK1CCNB1CCNA2CDK2CDK7 | |
| SCHEMBL5228023 | 0.78 | CA2 (0.49) | FFAR4MAPTHTTALDH1A1HPGD | |
| SCHEMBL5232126 | 0.78 | EPAS1 (0.40) | FFAR4MAPTHTTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519932-B1 | BISARYLSULFONAMIDE COMPOUNDS AND THEIR USE IN CANCER THERAPY | CYCLACEL LTD (GB) | 2007-10-03 | — | — | EP | claimed |