Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228646 | 0.87 | ACHE (0.38) | KDM4EALDH1A1LMNA | |
| SCHEMBL5226491 | 0.87 | ACHE (0.38) | KDM4EALDH1A1LMNA | |
| SCHEMBL6638381 | 0.83 | GHSR (0.39) | KDM4EALDH1A1MAPTMGLLGHSR | |
| SCHEMBL7592436 | 0.82 | AKT1 (0.42) | — | |
| SCHEMBL7015726 | 0.82 | AKT1 (0.42) | — | |
| SCHEMBL6475038 | 0.80 | L3MBTL1 (0.37) | ALDH1A1TSHRGRM4LMNA | |
| SCHEMBL5225204 | 0.80 | L3MBTL1 (0.37) | ALDH1A1TSHRGRM4LMNA | |
| SCHEMBL5227898 | 0.78 | GHSR (0.45) | SCDGHSR | |
| SCHEMBL5224946 | 0.78 | GHSR (0.45) | SCDGHSR | |
| SCHEMBL3840114 | 0.78 | GHSR (0.55) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001970-B1 | DIPEPTIDE DERIVATIVES AS GROWTH HORMONE SECRETAGOGUES | PFIZER (US) | 2007-03-07 | — | — | EP | disclosed |