Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | PDE6A | P16499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3000679 | 0.89 | PDE5A (0.39) | PDE5AGRIN2BGRIN1CYP3A4CYP2C19 | |
| SCHEMBL5233817 | 0.86 | CYP2D6 (0.38) | GRIN2BGRIN1CYP2D6HRH1KCNH2 | |
| SCHEMBL5232300 | 0.86 | CYP2D6 (0.33) | GRIN2BGRIN1CYP2D6HRH1KCNH2 | |
| SCHEMBL5231299 | 0.84 | CYP2D6 (0.33) | GRIN2BGRIN1CYP2D6HRH1KCNH2 | |
| SCHEMBL5228717 | 0.84 | ALDH1A1 (0.38) | CYP2D6HRH1KCNH2 | |
| SCHEMBL5233042 | 0.83 | CYP2D6 (0.39) | GRIN2BGRIN1CYP2D6HRH1KCNH2 | |
| SCHEMBL5231760 | 0.83 | SCN9A (0.37) | GRIN2BGRIN1CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL5231037 | 0.82 | GRIN2B (0.38) | GRIN2BGRIN1CYP2D6HRH1KCNH2 | |
| SCHEMBL5227499 | 0.81 | TSPO (0.34) | GRIN2BGRIN1CYP2D6HRH1KCNH2 | |
| SCHEMBL5229499 | 0.81 | CYP2D6 (0.34) | GRIN2BGRIN1CYP2D6HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |