Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231299 | 0.91 | CYP2D6 (0.33) | CYP2D6HRH1KCNH2MAPTGRIN1 | |
| SCHEMBL5233817 | 0.90 | CYP2D6 (0.38) | CYP2D6HRH1KCNH2MAPTGRIN1 | |
| SCHEMBL5228717 | 0.89 | ALDH1A1 (0.38) | CYP2D6HRH1KCNH2MAPT | |
| SCHEMBL5231037 | 0.89 | GRIN2B (0.38) | CYP2D6HRH1KCNH2MAPTGRIN1 | |
| SCHEMBL3000874 | 0.88 | MAPT (0.33) | CYP2D6HRH1KCNH2MAPTGRIN1 | |
| SCHEMBL5227499 | 0.87 | TSPO (0.34) | CYP2D6HRH1KCNH2MAPTGRIN1 | |
| SCHEMBL5232300 | 0.84 | CYP2D6 (0.33) | CYP2D6HRH1KCNH2MAPTGRIN1 | |
| SCHEMBL5231760 | 0.83 | SCN9A (0.37) | CYP2D6HRH1KCNH2MAPTGRIN1 | |
| SCHEMBL5229100 | 0.81 | PDE5A (0.39) | CYP2D6HRH1KCNH2GRIN1GRIN2B | |
| SCHEMBL5233042 | 0.80 | CYP2D6 (0.39) | CYP2D6HRH1KCNH2GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |