Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2992079 | 0.94 | MEN1 (0.36) | MEN1CYP3A4CYP2D6CYP2C19KMT2A | |
| SCHEMBL2996610 | 0.92 | OPRK1 (0.40) | MEN1CYP3A4CYP2D6CYP2C19KMT2A | |
| SCHEMBL13211483 | 0.85 | FABP4 (0.38) | HPGDFABP4KDM4E | |
| SCHEMBL27642142 | 0.85 | FABP4 (0.35) | FABP4 | |
| SCHEMBL13211498 | 0.85 | POLB (0.39) | MEN1KMT2AFABP4KDM4ESMN1; SMN2 | |
| SCHEMBL13211487 | 0.85 | ALDH1A1 (0.39) | CYP3A4HPGDFABP4KDM4E | |
| SCHEMBL2998608 | 0.85 | CNR1 (0.37) | MEN1KMT2AFABP4KDM4E | |
| SCHEMBL13211491 | 0.84 | TBXAS1 (0.46) | KDM4ESMN1; SMN2 | |
| SCHEMBL13211509 | 0.84 | FABP4 (0.34) | MEN1KMT2AHPGDFABP4OPRM1 | |
| SCHEMBL427108 | 0.83 | EGFR (0.45) | KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |