Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SPR | P35270 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784539 | 0.81 | MAPT (0.80) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12789658 | 0.76 | PPARG (0.64) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL5229664 | 0.76 | MAPT (0.97) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15761593 | 0.76 | PPARG (0.58) | KMT2AMEN1FFAR4 | |
| SCHEMBL20421277 | 0.74 | FFAR1 (0.56) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7089033 | 0.74 | TRPV1 (0.54) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12462888 | 0.74 | HTR6 (0.59) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL13605323 | 0.73 | ALDH1A1 (0.76) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30230090 | 0.73 | FFAR1 (0.63) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10706317 | 0.72 | TSHR (0.63) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519932-B1 | BISARYLSULFONAMIDE COMPOUNDS AND THEIR USE IN CANCER THERAPY | CYCLACEL LTD (GB) | 2007-10-03 | — | — | EP | claimed |