Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | ULK1 | O75385 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24477417 | 0.85 | TRPV1 (0.46) | TRPV1MAPTCNR2KDM1AKIF11 | |
| SCHEMBL24477512 | 0.85 | TRPV1 (0.46) | TRPV1MAPTCNR2KDM1AKIF11 | |
| SCHEMBL24777901 | 0.82 | ADRA2A (0.61) | MAPTADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL3996428 | 0.78 | TRPV1 (0.60) | TRPV1MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL4846626 | 0.76 | TRPV1 (0.71) | TRPV1MAPTADRA2AADRA2BADRA2C | |
| SCHEMBL1009963 | 0.75 | TRPV1 (0.62) | TRPV1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL656873 | 0.74 | SYK (0.66) | ULK1 | |
| SCHEMBL394467 | 0.74 | RAPGEF4 (0.59) | MAPTKIF11AKR1C3AKR1C2 | |
| SCHEMBL657416 | 0.74 | KDM1A (0.62) | MAPTADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL5229376 | 0.74 | MAPT (0.81) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363897-A2 | ANTAGONISTS OF MCP-1 FUNCTION AND METHODS OF USE THEREOF | TELIK, INC. (US) | 2003-11-26 | — | — | EP | claimed |
| WO-2002070509-A2 | ANTAGONISTS OF MCP-1 FUNCTION AND METHODS OF USE THEREOF | TELIK, INC. (US) | 2002-09-12 | — | — | WO | claimed |