Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231931 | 0.81 | ENPP1 (0.42) | MAPK1LMNAMEN1KMT2APDE2A | |
| SCHEMBL14337411 | 0.80 | ALDH1A1 (0.37) | CDK2GSK3BEGLN2MAPK1LMNA | |
| SCHEMBL5227382 | 0.80 | MEN1 (0.47) | CDK2GSK3BMAPK1LMNAMEN1 | |
| SCHEMBL7958939 | 0.79 | CDK2 (0.38) | CDK2GSK3BEGLN2MAPK1LMNA | |
| SCHEMBL5227148 | 0.78 | PDE2A (0.36) | MAPK1LMNAMEN1KMT2APDE2A | |
| SCHEMBL5228395 | 0.78 | PDE2A (0.36) | MAPK1LMNAMEN1KMT2APDE2A | |
| SCHEMBL5225477 | 0.78 | PDE2A (0.38) | MEN1KMT2APDE2A | |
| SCHEMBL5227316 | 0.78 | MBOAT4 (0.41) | PDE2AALDH1A1POLB | |
| SCHEMBL8807136 | 0.78 | NRP1 (0.41) | CDK2GSK3BEGLN2MAPK1LMNA | |
| SCHEMBL5225793 | 0.77 | PDE2A (0.35) | MAPK1PDE2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307172-B2 | 7-amino triazolopyrimidines for controlling harmful fungi | BASF AKTIENGESELLSCHAFT (DE) | 2007-12-11 | — | — | US | claimed |
| EP-1414302-B1 | 7-AMINO TRIAZOLOPYRIMIDINES FOR CONTROLLING HARMFUL FUNGI | BASF AG (DE) | 2007-03-21 | — | — | EP | claimed |