Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NRP1 | O14786 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4822465 | 0.98 | PDE2A (0.40) | NRP1USP2POLBRAB9ALMNA | |
| SCHEMBL4819307 | 0.88 | ALOX5 (0.42) | RAB9ALMNAALDH1A1KDM4EADORA1 | |
| SCHEMBL4818794 | 0.86 | ADORA3 (0.43) | USP2POLBRAB9ALMNAALDH1A1 | |
| SCHEMBL8805373 | 0.86 | USP2 (0.40) | NRP1USP2POLBRAB9ALMNA | |
| SCHEMBL8805553 | 0.85 | ALDH1A1 (0.47) | POLBRAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8640237 | 0.85 | ALDH1A1 (0.43) | USP2POLBLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8806276 | 0.84 | ADORA3 (0.42) | USP2POLBRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4821059 | 0.83 | RAB9A (0.43) | NRP1USP2POLBRAB9AKDM4E | |
| SCHEMBL7487750 | 0.83 | MAPK1 (0.37) | POLBLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7958939 | 0.82 | CDK2 (0.38) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550113-B1 | Triazolopyrimidine derivatives with fungicidal activity | SHELL INT RESEARCH (NL) | 1997-10-15 | — | — | EP | disclosed |
| EP-0782997-A2 | Triazolopyrimidine derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1997-07-09 | — | — | EP | disclosed |
| US-5593996-A | FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0550113-A2 | Triazolopyrimidine derivatives with fungicidal activity | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-07-07 | — | — | EP | disclosed |