Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27532545 | 0.89 | PDE4A (0.40) | TRPA1NFE2L2PLA2G7GRIN1GRIN2B | |
| SCHEMBL6311091 | 0.84 | KCNA3 (0.34) | TRPA1 | |
| SCHEMBL6439481 | 0.84 | KCNA3 (0.34) | TRPA1 | |
| SCHEMBL5231365 | 0.84 | GPR183 (0.34) | TRPA1NFE2L2NPC1MAPTRAB9A | |
| SCHEMBL5229485 | 0.84 | TRPA1 (0.44) | TRPA1NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL5230461 | 0.84 | KCNA3 (0.34) | TRPA1 | |
| SCHEMBL5231765 | 0.84 | GABRA1 (0.46) | TRPA1NFE2L2PTGS2JUN | |
| SCHEMBL27176003 | 0.84 | GABRA1 (0.46) | TRPA1NFE2L2PTGS2JUN | |
| SCHEMBL28684322 | 0.81 | GABRA1 (0.46) | TRPA1NFE2L2PTGS2JUN | |
| SCHEMBL5229721 | 0.81 | GABRA1 (0.46) | TRPA1NFE2L2PTGS2JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313741-B1 | FLUORINATED AND ALKYLATED ALDITOL DERIVATIVES AND POLYOLEFIN ARTICLES CONTAINING SAME | MILLIKEN & CO (US) | 2007-05-23 | — | — | EP | claimed |
| US-6906207-B2 | Polymer additive compositions and articles comprising novel fluorinated and alkylated alditol derivatives | MILLIKEN & COMPANY (US) | 2005-06-14 | — | — | US | claimed |
| US-20030181552-A1 | Polymer additive compositions and articles comprising novel fluorinated and alkylated alditol derivatives | ANDERSON JOHN D (US) | 2003-09-25 | — | — | US | claimed |
| EP-1313741-A2 | FLUORINATED AND ALKYLATED ALDITOL DERIVATIVES AND POLYOLEFIN ARTICLES CONTAINING SAME | Milliken & Company (US) | 2003-05-28 | — | — | EP | claimed |
| US-20020062034-A1 | Novel fluorinated and alkylated alditol derivatives and compositions and polyolefin articles containing same | MILLIKEN &COMPANY | 2002-05-23 | — | — | US | claimed |
| WO-2002020528-A2 | FLUORINATED AND ALKYLATED ALDITOL DERIVATIVES AND POLYOLEFIN ARTICLES CONTAINING SAME | MILLIKEN & COMPANY (US) | 2002-03-14 | — | — | WO | claimed |
| EP-1313741-B1 | FLUORINATED AND ALKYLATED ALDITOL DERIVATIVES AND POLYOLEFIN ARTICLES CONTAINING SAME | MILLIKEN & CO (US) | 2007-05-23 | — | — | EP | disclosed |
| US-6906207-B2 | Polymer additive compositions and articles comprising novel fluorinated and alkylated alditol derivatives | MILLIKEN & COMPANY (US) | 2005-06-14 | — | — | US | disclosed |
| US-6849747-B2 | Fluorinated and alkylated dibenzylidene alditol derivatives | MILLIKEN & COMPANY (US) | 2005-02-01 | — | — | US | disclosed |
| US-6838568-B2 | Fluorinated and alkylated alditol derivatives and compositions and polyolefin articles containing same | MILLIKEN & COMPANY (US) | 2005-01-04 | — | — | US | disclosed |
| US-20040116515-A1 | Novel fluorinated and alkylated dibenzylidene alditol derivatives | ANDERSON JOHN D (US) | 2004-06-17 | — | — | US | disclosed |
| US-20040110967-A1 | Novel fluorinated and alkylated dibenzylidene alditol derivatives | ANDERSON JOHN D (US) | 2004-06-10 | — | — | US | disclosed |
| US-6734238-B2 | RADIATION TRANSPARENT; ANTIPERSPIRANT GEL | MILLIKEN & COMPANY | 2004-05-11 | — | — | US | disclosed |
| US-20030181552-A1 | Polymer additive compositions and articles comprising novel fluorinated and alkylated alditol derivatives | ANDERSON JOHN D (US) | 2003-09-25 | — | — | US | disclosed |
| US-20030181534-A1 | Gels comprising novel fluorinated and alkylated alditol derivatives | ANDERSON JOHN D (US) | 2003-09-25 | — | — | US | disclosed |
| US-20030171462-A1 | Polyolefin compositions and articles comprising novel fluorinated and alkylated alditol derivatives | ANDERSON JOHN D (US) | 2003-09-11 | — | — | US | disclosed |
| US-20030139612-A1 | Novel fluorinated and alkylated alditol derivatives and compositions and polyolefin articles containing same | ANDERSON JOHN D (US) | 2003-07-24 | — | — | US | disclosed |
| EP-1313741-A2 | FLUORINATED AND ALKYLATED ALDITOL DERIVATIVES AND POLYOLEFIN ARTICLES CONTAINING SAME | Milliken & Company (US) | 2003-05-28 | — | — | EP | disclosed |
| US-20020062034-A1 | Novel fluorinated and alkylated alditol derivatives and compositions and polyolefin articles containing same | MILLIKEN &COMPANY | 2002-05-23 | — | — | US | disclosed |
| WO-2002020528-A2 | FLUORINATED AND ALKYLATED ALDITOL DERIVATIVES AND POLYOLEFIN ARTICLES CONTAINING SAME | MILLIKEN & COMPANY (US) | 2002-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139612-A1 | Novel fluorinated and alkylated alditol derivatives and compositions and polyolefin articles containing same | ALDOA, SORD, ADH1A | TRPA1 2462/4885NFE2L2 3700/4885PLA2G7 893/4885 |
| US-20040110967-A1 | Novel fluorinated and alkylated dibenzylidene alditol derivatives | ALDOA, DERA, SORD | TRPA1 2764/4885NFE2L2 3433/4885PLA2G7 1952/4885 |
| US-20020062034-A1 | Novel fluorinated and alkylated alditol derivatives and compositions and polyolefin articles containing same | ALDOA, SORD, DERA | TRPA1 2333/4885NFE2L2 3735/4885PLA2G7 965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.