Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232470 | 0.85 | CCR5 (0.54) | CCR5CCL5 | |
| SCHEMBL4695956 | 0.84 | HCRTR1 (0.37) | CCR5 | |
| SCHEMBL5237860 | 0.82 | CCL5 (0.43) | CCR5CCL5 | |
| SCHEMBL5234982 | 0.79 | CCR5 (0.42) | CCR5CCL5 | |
| SCHEMBL4697511 | 0.78 | ALDH1A1 (0.41) | CCR5 | |
| SCHEMBL4690328 | 0.78 | CCR5 (0.52) | CCR5CCL5 | |
| SCHEMBL5237872 | 0.78 | CCL5 (0.40) | CCL5 | |
| SCHEMBL5233029 | 0.78 | CCR5 (0.44) | CCR5 | |
| SCHEMBL5240008 | 0.78 | ALDH1A1 (0.48) | CCR5 | |
| SCHEMBL5235577 | 0.77 | CCL5 (0.38) | CCR5CCL5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-A2 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-03-14 | — | — | EP | claimed |
| WO-2005121145-A2 | OCTAHYDRO-PYRROLO[3,4-C] DERIVATIVES AND THEIR USE AS ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-12-22 | — | — | WO | claimed |