Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17911707 | 0.98 | MEN1 (0.40) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| Iodide SCHEMBL7024152 | 0.87 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| Iodide SCHEMBL8745570 | 0.83 | MEN1 (0.33) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| Iodide SCHEMBL8072633 | 0.82 | MEN1 (0.35) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8745599 | 0.82 | MEN1 (0.32) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11314920 | 0.81 | MEN1 (0.31) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL8745629 | 0.80 | MEN1 (0.36) | MEN1KMT2AALDH1A1NPC1MAPT | |
| Iodide SCHEMBL3807575 | 0.80 | CHAT (0.37) | MEN1KMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL7544937 | 0.78 | CHAT (0.35) | ALDH1A1MAPTSMN1; SMN2KDM4EKDM1A | |
| SCHEMBL7904469 | 0.71 | ESR1 (0.45) | MEN1KMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362645-A | Temperature indicating compositions of matter | AKZONA, INC. (US) | 1982-12-07 | — | — | US | claimed |
| US-4345470-A | All plastic disposable thermometer | AKZONA INCORPORATED (US) | 1982-08-24 | — | — | US | claimed |
| US-4339207-A | Temperature indicating compositions of matter | AKZONA INCORPORATED (US) | 1982-07-13 | — | — | US | claimed |
| US-4232552-A | THERMOCHROMISM, DISPOSABLE THERMOMETERS | AKZONA INCORPORATED (US) | 1980-11-11 | — | — | US | claimed |
| US-11998302-B2 | Thermographic device for measurement of differential temperatures in tissue | WELWAZE MEDICAL INC. (US) | 2024-06-04 | — | — | US | disclosed |
| US-20230200662-A1 | THERMOGRAPHIC DEVICE FOR MEASUREMENT OF DIFFERENTIAL TEMPERATURES IN TISSUE | WELWAZE MEDICAL INC. (US) | 2023-06-29 | — | — | US | disclosed |
| US-11445917-B2 | Thermographic device for measurement of differential temperatures in tissue | WELWAZE MEDICAL INC. (US) | 2022-09-20 | — | — | US | disclosed |
| EP-3758592-A2 | THERMOGRAPHIC DEVICE FOR MEASUREMENT OF DIFFERENTIAL TEMPERATURES IN TISSUE | Welwaze Medical Inc. (US) | 2021-01-06 | — | — | EP | disclosed |
| US-20190209019-A1 | THERMOGRAPHIC DEVICE FOR MEASUREMENT OF DIFFERENTIAL TEMPERATURES IN TISSUE | ZICHY, MARLENE (AR) | 2019-07-11 | — | — | US | disclosed |
| WO-2019113460-A2 | THERMOGRAPHIC DEVICE FOR MEASUREMENT OF DIFFERENTIAL TEMPERATURES IN TISSUE | WELWAZE MEDICAL INC. (US) | 2019-06-13 | — | — | WO | disclosed |
| EP-0684463-B1 | Temperature indicating device and composition for use therein | 3M INNOVATIVE PROPERTIES CO (US) | 2007-09-05 | — | — | EP | disclosed |
| US-6770102-B1 | AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS; DOES NOT REQUIRE OXIDIZING AGENT; BRILLIANCE; COLOR DEPTH; WIDE VARIETY OF SHADES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-08-03 | — | — | US | disclosed |
| US-5816707-A | Reversible chemical thermometer | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0684463-A1 | Temperature indicating device and composition for use therein | PyMaH Corporation (US) | 1995-11-29 | — | — | EP | disclosed |
| US-5401100-A | Axillary thermometer packaging | PYMAH CORPORATION (US) | 1995-03-28 | — | — | US | disclosed |
| US-5094545-A | Solid solution with nucleating agent and indicator dye | PYMA CORPORATION (US) | 1992-03-10 | — | — | US | disclosed |
| US-4397570-A | HIGH SPEED REVERSING; RETENTION OF LOW-TEMPERATURE PROPERTIES | PYMAH CORPORATION (US) | 1983-08-09 | — | — | US | disclosed |
| US-4362645-A | Temperature indicating compositions of matter | AKZONA, INC. (US) | 1982-12-07 | — | — | US | disclosed |
| US-4339207-A | Temperature indicating compositions of matter | AKZONA INCORPORATED (US) | 1982-07-13 | — | — | US | disclosed |
| US-4232552-A | THERMOCHROMISM, DISPOSABLE THERMOMETERS | AKZONA INCORPORATED (US) | 1980-11-11 | — | — | US | disclosed |