Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL3807575 | 0.98 | CHAT (0.37) | CHATTSHRACHEHRH1PDE4D | |
| SCHEMBL7908969 | 0.83 | PTGS2 (0.41) | ALDH1A1AKR1C3KDM4ESMN1; SMN2MAPT | |
| SCHEMBL17911707 | 0.80 | MEN1 (0.40) | TSHRALDH1A1AKR1C3KDM4ESMN1; SMN2 | |
| Iodide SCHEMBL5229857 | 0.78 | MEN1 (0.42) | CHATTSHRALDH1A1AKR1C3KDM4E | |
| SCHEMBL8745629 | 0.75 | MEN1 (0.36) | TSHRALDH1A1AKR1C3KDM1AMAPT | |
| Iodide SCHEMBL8072633 | 0.74 | MEN1 (0.35) | TSHRALDH1A1AKR1C3SMN1; SMN2KDM1A | |
| SCHEMBL2845203 | 0.72 | AKR1C1 (0.45) | TSHRALDH1A1AKR1C3MAPT | |
| SCHEMBL7904469 | 0.72 | ESR1 (0.45) | TSHRALDH1A1AKR1C3SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL10347945 | 0.72 | TSHR (0.44) | CHATTSHRACHEHRH1PDE4D | |
| Iodide SCHEMBL7120383 | 0.71 | ACHE (0.49) | ACHEALDH1A1KDM4ESMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210596-A2 | METHODS FOR ASSAYING SUBCELLULAR CONDITIONS USING ENERGY TRANSFER | MITOKOR (US) | 2002-06-05 | — | — | EP | disclosed |
| WO-2000079274-A2 | METHODS FOR ASSAYING SUBCELLULAR CONDITIONS USING ENERGY TRANSFER | MITOKOR (US) | 2000-12-28 | — | — | WO | disclosed |