Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AGER | Q15109 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2997212 | 0.87 | CNR1 (0.37) | CNR1CYP3A4CYP2C19TACR1TP53 | |
| SCHEMBL5231069 | 0.86 | LSS (0.36) | CNR1TACR1HRH3LSSALDH1A1 | |
| SCHEMBL5230079 | 0.85 | MMP2 (0.35) | CNR1CYP3A4CYP2C19TACR1 | |
| SCHEMBL5233254 | 0.85 | TACR1 (0.36) | CNR1CYP3A4CYP2C19TACR1TP53 | |
| SCHEMBL5227454 | 0.83 | ALDH1A1 (0.34) | CNR1TACR1ALDH1A1 | |
| SCHEMBL5228235 | 0.82 | EGFR (0.39) | TACR1TP53MAPTALDH1A1 | |
| SCHEMBL5234741 | 0.81 | CNR1 (0.34) | CNR1CYP3A4CYP2C19TP53MAPT | |
| SCHEMBL5227012 | 0.77 | CYP3A4 (0.40) | CNR1CYP3A4CYP2C19TACR1PTGDR | |
| SCHEMBL3001005 | 0.75 | MEN1 (0.36) | CNR1TACR1HRH3ALDH1A1 | |
| SCHEMBL2996688 | 0.74 | MMP2 (0.35) | CNR1CYP3A4CYP2C19TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |