Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233254 | 0.95 | TACR1 (0.36) | LSSMEN1KMT2ATACR1CNR1 | |
| SCHEMBL5227454 | 0.91 | ALDH1A1 (0.34) | MEN1KMT2ATACR1MCHR1CNR1 | |
| SCHEMBL5230079 | 0.90 | MMP2 (0.35) | TACR1CNR1TRPV4HTR2A | |
| SCHEMBL3001005 | 0.87 | MEN1 (0.36) | MEN1KMT2ATACR1HRH3MCHR1 | |
| SCHEMBL5229977 | 0.86 | CNR1 (0.36) | LSSTACR1HRH3CNR1ALDH1A1 | |
| SCHEMBL5237010 | 0.83 | EGFR (0.39) | KMT2ATACR1KDM4EALDH1A1MAPK1 | |
| SCHEMBL2998567 | 0.82 | TACR1 (0.37) | MEN1KMT2ATACR1CNR1ALDH1A1 | |
| SCHEMBL5234741 | 0.81 | CNR1 (0.34) | CNR1KDM4EALDH1A1 | |
| SCHEMBL5230751 | 0.80 | EGFR (0.38) | KMT2ATACR1POLBMAPK1 | |
| SCHEMBL2997420 | 0.79 | MEN1 (0.36) | MEN1KMT2ATACR1MCHR1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664059-B1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2007-09-12 | — | — | EP | claimed |