Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5234394 | 0.81 | SLC6A3 (0.38) | HSD11B1MAOBKCNN4CES2CES1 | |
| SCHEMBL3140331 | 0.77 | PARP10 (0.46) | MAOBALDH1A1MAOACES2CES1 | |
| SCHEMBL7805830 | 0.76 | HSD11B1 (0.42) | HSD11B1PTGS2 | |
| SCHEMBL5202712 | 0.74 | SLC6A4 (0.45) | — | |
| SCHEMBL2701756 | 0.71 | ALOX5 (0.49) | HSD11B1ALDH1A1 | |
| SCHEMBL379020 | 0.71 | HSD11B1 (0.49) | HSD11B1MAOBKCNN4ALDH1A1MAOA | |
| SCHEMBL19817411 | 0.70 | IDO1 (0.43) | HSD11B1MAOBKCNN4ALDH1A1MAOA | |
| Hydrochloric Acid SCHEMBL5794598 | 0.69 | HSD11B1 (0.48) | HSD11B1MAOBKCNN4ALDH1A1MAOA | |
| SCHEMBL3704068 | 0.69 | AKR1C1 (0.38) | HSD11B1MAOB | |
| SCHEMBL15874310 | 0.69 | KMT2A (0.43) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819672-A1 | INDOLE-2-CARBOXYLIC ACID AMIDES | Prosidion Limited (GB) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056815-A1 | INDOLE-2-CARBOXYLIC ACID AMIDES | PROSIDION LIMITED (GB) | 2006-06-01 | — | — | WO | disclosed |