Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHRND | Q07001 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5234394 | 0.77 | SLC6A3 (0.38) | SLC6A4SLC6A2SLC6A3CHRNA1CHRNG | |
| SCHEMBL5230381 | 0.74 | HSD11B1 (0.40) | — | |
| SCHEMBL11106003 | 0.71 | LMNA (0.53) | SLC6A4SLC6A2SLC6A3CCR2 | |
| SCHEMBL8242396 | 0.71 | LMNA (0.56) | SLC6A4SLC6A2SLC6A3CCR2 | |
| SCHEMBL3140331 | 0.70 | PARP10 (0.46) | — | |
| SCHEMBL5202717 | 0.69 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17414156 | 0.69 | CCR2 (0.42) | SLC6A4SLC6A2SLC6A3NPSR1CHRNA1 | |
| SCHEMBL6973280 | 0.68 | SLC6A2 (0.37) | SLC6A4SLC6A2SLC6A3CHRNA1CHRNG | |
| SCHEMBL2738480 | 0.68 | SLC6A2 (0.59) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL13365220 | 0.67 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819672-A1 | INDOLE-2-CARBOXYLIC ACID AMIDES | Prosidion Limited (GB) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056815-A1 | INDOLE-2-CARBOXYLIC ACID AMIDES | PROSIDION LIMITED (GB) | 2006-06-01 | — | — | WO | disclosed |