Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 3/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5230311 | 0.87 | PLAU (0.43) | ACLYTP53MAPTALDH1A1PTGES2 | |
| SCHEMBL5229967 | 0.81 | P2RX1 (0.47) | FBP1ACLYTP53MAPTRAD51 | |
| SCHEMBL5231576 | 0.80 | MAPT (0.49) | FBP1TP53MAPTALDH1A1RAD51 | |
| SCHEMBL5229199 | 0.77 | MAPT (0.68) | TP53MAPTALDH1A1LMNATSHR | |
| SCHEMBL5229776 | 0.77 | MEN1 (0.55) | FBP1TP53MAPTTSHR | |
| SCHEMBL4879586 | 0.77 | ALDH1A1 (0.52) | FBP1TP53MAPTALDH1A1RAD51 | |
| SCHEMBL1510259 | 0.76 | FBP1 (0.48) | FBP1ACLYTP53MAPTRAD51 | |
| SCHEMBL5233848 | 0.76 | ACLY (0.39) | ACLYTP53ALDH1A1FKBP1A | |
| SCHEMBL5230621 | 0.73 | CES1 (0.50) | TP53MAPTALDH1A1TSHRPGR | |
| SCHEMBL9997253 | 0.73 | PFKFB3 (0.63) | FBP1ACLYTP53MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519932-B1 | BISARYLSULFONAMIDE COMPOUNDS AND THEIR USE IN CANCER THERAPY | CYCLACEL LTD (GB) | 2007-10-03 | — | — | EP | claimed |