Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232572 | 1.00 | MAPT (0.39) | MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5231227 | 0.86 | ALDH1A1 (0.39) | MAPTALDH1A1SMN1; SMN2L3MBTL1CA2 | |
| SCHEMBL7318709 | 0.86 | ALDH1A1 (0.39) | MAPTALDH1A1SMN1; SMN2L3MBTL1CA2 | |
| SCHEMBL5238517 | 0.86 | ALDH1A1 (0.39) | MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5238511 | 0.86 | ALDH1A1 (0.39) | MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL7330871 | 0.84 | ALDH1A1 (0.46) | MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL7330866 | 0.84 | ALDH1A1 (0.46) | MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL8691503 | 0.80 | DRD2 (0.39) | MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5236789 | 0.79 | KMT2A (0.44) | MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5234520 | 0.75 | ALDH1A1 (0.40) | MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804440-B1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | WYETH CORP (US) | 2007-12-19 | — | — | EP | disclosed |
| US-5719278-A | TREATING EXCESS RENAL REABSORPTION OF WATER | AMERICAN CYANAMID COMPANY (US) | 1998-02-17 | — | — | US | disclosed |
| WO-1996022295-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |
| US-5532235-A | TO TREAT EXCESS RENAL REABSORPTION | AMERICAN CYANAMID COMPANY (US) | 1996-07-02 | — | — | US | disclosed |