Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.53 |
| ▸ | LIPE | Q05469 | 1/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922515 | 0.95 | LMNA (0.61) | MAPTLMNAALDH1A1GPR119LIPE | |
| SCHEMBL5233751 | 0.86 | L3MBTL1 (0.66) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL5231271 | 0.85 | MAPT (0.67) | MAPTLMNAALDH1A1GPR119PDK2 | |
| SCHEMBL5230610 | 0.85 | ALDH1A1 (0.61) | MAPTLMNAALDH1A1GPR119PDK2 | |
| SCHEMBL3938884 | 0.84 | MAPT (0.57) | MAPTLMNAALDH1A1GPR119LIPE | |
| SCHEMBL5543519 | 0.84 | GPR119 (0.55) | MAPTLMNAALDH1A1GPR119LIPE | |
| SCHEMBL31466222 | 0.84 | CKS1B (0.45) | MAPTLMNAALDH1A1GPR119LIPE | |
| SCHEMBL5231173 | 0.83 | GPR119 (0.70) | MAPTLMNAALDH1A1GPR119PDK2 | |
| SCHEMBL13281422 | 0.83 | MAPT (0.62) | MAPTLMNAALDH1A1GPR119PDK2 | |
| SCHEMBL5233944 | 0.83 | MAPT (0.56) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | SANKYO COMPANY, LIMITED (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219234-A1 | Thienopyridine Derivatives | RASGRP1, NRAS, HRH3 | MAPT 4452/4885LMNA 4549/4885ALDH1A1 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.