Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UQCRB | P14927 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | PKM | P14618 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.73 |
| ▸ | IL1RN | P18510 | 1/20 | 0.73 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.73 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CA2 | P00918 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | GFER | P55789 | 2/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.62 |
| ▸ | STAT3 | P40763 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28178888 | 0.98 | UQCRB (0.77) | UQCRBMEN1KMT2APKMALDH1A1 | |
| SCHEMBL27428246 | 0.98 | UQCRB (0.77) | UQCRBMEN1KMT2APKMALDH1A1 | |
| SCHEMBL930801 | 0.92 | UQCRB (0.80) | UQCRBMEN1KMT2APKMALDH1A1 | |
| SCHEMBL1592323 | 0.90 | UQCRB (0.76) | UQCRBMEN1KMT2APKMALDH1A1 | |
| SCHEMBL810795 | 0.89 | KMT2A (0.91) | UQCRBMEN1KMT2APKMALDH1A1 | |
| SCHEMBL6296969 | 0.89 | UQCRB (1.00) | UQCRBMEN1KMT2APKMALDH1A1 | |
| SCHEMBL18995909 | 0.86 | STAT3 (0.64) | UQCRBMEN1KMT2APKMALDH1A1 | |
| SCHEMBL9001182 | 0.85 | KMT2A (1.00) | UQCRBMEN1KMT2APKMALDH1A1 | |
| SCHEMBL25031372 | 0.85 | KEAP1 (1.00) | MEN1KMT2APKMALDH1A1KEAP1 | |
| Phenyl(Phenylsulfonyl)Amine SCHEMBL114765 | 0.85 | KEAP1 (1.00) | MEN1KMT2APKMALDH1A1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1060 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-216855723-U | Low-temperature crystallization kettle for synthesizing N- (4-hydroxyphenyl) benzene sulfonamide | 上海优合生物科技有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-213408678-U | Continuous operation device for synthesizing N- (4-hydroxyphenyl) benzenesulfonamide | 上海优合生物科技有限公司 | 2021-06-11 | — | — | CN | claimed |
| US-10646482-B2 | Nitrogen-containing heteroaryl compounds and methods of use thereof | FIBROGEN, INC. (US) | 2020-05-12 | — | — | US | claimed |
| US-20190240213-A1 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | FIBROGEN, INC. | 2019-08-08 | — | — | US | claimed |
| US-10092558-B2 | Nitrogen-containing heteroaryl compounds and methods of use thereof | FIBROGEN, INC. (US) | 2018-10-09 | — | — | US | claimed |
| US-20170035747-A1 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | FIBROGEN, INC. | 2017-02-09 | — | — | US | claimed |
| WO-2015095757-A1 | TREATMENT OF RETINOPATHY OF PREMATURITY (ROP) | THE CLEVELAND CLINIC FOUNDATION (US) | 2015-06-25 | — | — | WO | claimed |
| CN-102977015-B | Nitrogen-containing heteroaryl compounds and their use in increasing endogeneous erythropoietin | FIBROGEN INC | 2015-05-06 | — | — | CN | claimed |
| US-8916585-B2 | Nitrogen-containing heteroaryl compounds and methods of use thereof | FIBROGEN, INC. (US) | 2014-12-23 | — | — | US | claimed |
| US-20130178417-A1 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | FIBROGEN, INC. | 2013-07-11 | — | — | US | claimed |
| EP-0929603-B1 | PLASTICISED POLYMER COMPOSITIONS | UCB SA (BE) | 2003-12-03 | — | — | EP | claimed |
| US-6624218-B2 | A blend comprising aromatic plasticizer benzenesulphonamides and semi-crystalline polymer; exhibits a processing temperature equal to or greater than 220 degrees C.; melt material for extrusion and injection molding | UCB, S.A. (BE) | 2003-09-23 | — | — | US | claimed |
| US-20020165301-A1 | Plasticized polymer compositions | UCB, S.A. | 2002-11-07 | — | — | US | claimed |
| US-6380146-B1 | FOR BLEACHING STAINS ON FABRICS DURING WASHING, WITHOUT PROVOKING DYE DAMAGE | UNILEVER HOME & PERSONAL CARE USA A DIVISION OF CONOPCO, INC. | 2002-04-30 | — | — | US | claimed |
| EP-1187899-A1 | METHOD AND COMPOSITION FOR ENHANCING THE ACTIVITY OF AN ENZYME | UNILEVER N.V. (NL) | 2002-03-20 | — | — | EP | claimed |
| WO-2001000769-A1 | METHOD AND COMPOSITION FOR ENHANCING THE ACTIVITY OF AN ENZYME | UNILEVER N.V. (NL) | 2001-01-04 | — | — | WO | claimed |
| WO-2001000768-A1 | BLEACHING DETERGENT COMPOSITIONS | UNILEVER N.V. (NL) | 2001-01-04 | — | — | WO | claimed |
| EP-0929603-A1 | PLASTICISED POLYMER COMPOSITIONS | UCB, S.A. (BE) | 1999-07-21 | — | — | EP | claimed |
| WO-1998014513-A1 | PLASTICISED POLYMER COMPOSITIONS | UCB, S.A. (BE) | 1998-04-09 | — | — | WO | claimed |
| US-4155761-A | TELLURIUM COORDINATION COMPOUND AND REDUCING AGENT | EASTMAN KODAK COMPANY (US) | 1979-05-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130178417-A1 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | HIF1AN, EGLN3, EGLN2 | UQCRB 2339/4885MEN1 4467/4885KMT2A 2350/4885 |
| US-20170035747-A1 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | HIF1AN, EGLN3, EGLN2 | UQCRB 2339/4885MEN1 4467/4885KMT2A 2350/4885 |
| US-10646482-B2 | Nitrogen-containing heteroaryl compounds and methods of use thereof | HIF1AN, HIF1A, EGLN2 | UQCRB 2208/4885MEN1 4223/4885KMT2A 2002/4885 |
| US-20190240213-A1 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | HIF1AN, EGLN3, EGLN2 | UQCRB 2339/4885MEN1 4467/4885KMT2A 2350/4885 |
| US-10092558-B2 | Nitrogen-containing heteroaryl compounds and methods of use thereof | HIF1AN, HIF1A, EGLN2 | UQCRB 2208/4885MEN1 4223/4885KMT2A 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.