Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | LIPE | Q05469 | 5/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | GIPR | P48546 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 4/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5236675 | 0.91 | NOTUM (0.40) | CHRM4 | |
| SCHEMBL5231923 | 0.89 | TRPA1 (0.35) | LIPEPTGDR2 | |
| SCHEMBL5234129 | 0.89 | ADORA3 (0.37) | — | |
| SCHEMBL5228551 | 0.88 | CHRM4 (0.39) | CHRM4EPHX2LIPEGCGRGIPR | |
| SCHEMBL5228545 | 0.88 | CHRM4 (0.39) | CHRM4EPHX2LIPEGCGRGIPR | |
| SCHEMBL5234466 | 0.87 | APP (0.36) | — | |
| SCHEMBL5236797 | 0.87 | — | — | |
| SCHEMBL5236128 | 0.87 | NPC1 (0.34) | — | |
| SCHEMBL5233446 | 0.87 | NPC1 (0.35) | — | |
| SCHEMBL5232338 | 0.86 | S1PR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730116-B1 | 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORP (US) | 2007-09-05 | — | — | EP | claimed |