Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ME2 | P23368 | 2/20 | 0.35 |
| ▸ | ME1 | P48163 | 2/20 | 0.35 |
| ▸ | ME3 | Q16798 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5234755 | 0.94 | EGLN1 (0.39) | EGLN1DGAT1KCNH2MGLLRAB9A | |
| SCHEMBL5231079 | 0.90 | DGAT1 (0.39) | DGAT1KCNH2MGLLCNR2ADORA2A | |
| SCHEMBL5238354 | 0.88 | MAPT (0.40) | DGAT1KCNH2MGLL | |
| SCHEMBL5235446 | 0.86 | ALDH1A1 (0.37) | DRD2 | |
| SCHEMBL5237009 | 0.86 | DGAT1 (0.39) | DGAT1KCNH2CNR2 | |
| SCHEMBL5238953 | 0.86 | TEK (0.37) | PANK3 | |
| SCHEMBL5238526 | 0.85 | PANK3 (0.39) | RAB9APANK3DRD2 | |
| SCHEMBL5238848 | 0.83 | EGLN1 (0.42) | EGLN1DGAT1ME2ME1ME3 | |
| SCHEMBL5237586 | 0.83 | KDM4E (0.40) | DGAT1KCNH2MGLLCNR2 | |
| SCHEMBL5239098 | 0.82 | MEN1 (0.39) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701946-B1 | DERIVATIVES OF 1-PIPERAZINE- AND 1-HOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS INHIBITORS OF THE FAAH ENZYME | SANOFI AVENTIS (FR) | 2007-12-19 | — | — | EP | claimed |