SCHEMBL523681

SCHEMBL523681

CO[SiH2]Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.42
LTA4H P09960 1/20 0.41
TSHR P16473 4/20 0.40
CALM1 P0DP23 1/20 0.39
ALDH1A1 P00352 3/20 0.37
IDO1 P14902 2/20 0.37
LOXL2 Q9Y4K0 1/20 0.36
TRPA1 O75762 1/20 0.36
CA4 P22748 1/20 0.36
KDM4E B2RXH2 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
AGXT P21549 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethylamine SCHEMBL27844815 0.88 GAA (0.39) TP53LTA4HTSHRALDH1A1TRPA1
SCHEMBL320639 0.79 TSHR (0.43) TP53TSHRCALM1ALDH1A1IDO1
SCHEMBL15102980 0.78 AGXT (0.43) TP53IDO1TDP1AGXTMAPT
SCHEMBL2495545 0.76 ALDH1A1 (0.42) TP53LTA4HALDH1A1IDO1LOXL2
SCHEMBL2239541 0.76 TP53 (0.44) TP53LTA4HTSHRCALM1ALDH1A1
SCHEMBL22661049 0.76 CA2 (0.39) TP53LTA4HTSHRCALM1ALDH1A1
SCHEMBL2032974 0.75 CALM1 (0.50) TP53TSHRCALM1ALDH1A1IDO1
SCHEMBL116134 0.75 TSHR (0.40) TP53TSHRCALM1ALDH1A1IDO1
SCHEMBL29235855 0.75 TSHR (0.41) TP53TSHRCALM1TRPA1
SCHEMBL29235981 0.75 AOC3 (0.40) TP53TSHRCALM1ALDH1A1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111482199-B Olefin cracking catalyst, preparation method thereof and olefin cracking method 中国石油大学(北京) 2023-12-15 CN disclosed
WO-2022230944-A1 PLANARIZING FILM MANUFACTURING METHOD, PLANARIZING FILM MATERIAL, AND PLANARIZING FILM 東ソー株式会社 2022-11-03 WO disclosed
CN-111482199-A Olefin cracking catalyst, preparation method thereof and olefin cracking method 中国石油大学(北京) 2020-08-04 CN disclosed
EP-2432843-B1 ONE-COMPONENT EPOXY COATING COMPOSITIONS PPG IND OHIO INC (US) 2020-05-20 EP disclosed
EP-2190928-B1 ONE COMPONENT POLYSILOXANE COATING COMPOSITIONS AND RELATED COATED SUBSTRATES PPG IND OHIO INC (US) 2018-04-18 EP disclosed
US-9862803-B2 Branched organopolysiloxane and a method for preparing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
US-9663598-B2 Organosilicon compound-containing thermosetting composition and cured product thereof TOAGOSEI CO., LTD. (JP) 2017-05-30 US disclosed
US-20160304675-A1 BRANCHED ORGANOPOLYSILOXANE AND A METHOD FOR PREPARING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-10-20 US disclosed
US-20160200842-A1 ORGANOSILICON COMPOUND-CONTAINING THERMOSETTING COMPOSITION AND CURED PRODUCT THEREOF TOAGOSEI CO., LTD. (JP) 2016-07-14 US disclosed
EP-2128897-B1 SILICON DIELECTRIC TREATING AGENT FOR USE AFTER ETCHING, PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJITSU LTD (JP) 2015-05-06 EP disclosed
US-20070104896-A1 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-05-10 US disclosed
US-20070103786-A1 Optical film, anti-reflection film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2007-05-10 US disclosed
US-20070058250-A1 Optical film, antireflection film, polarizing plate using the same and display device FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 US disclosed
US-20070048457-A1 Producing method of film having coated layer, film having coated layer, optical film, polarizing plate and liquid crystal display FUJI FILM CORPORATION (JP) 2007-03-01 US disclosed
EP-1746132-A1 SILICON-CONTAINING CURABLE COMPOSITION AND CURED OBJECT OBTAINED BY THERMALLY CURING THE SAME Adeka Corporation (JP) 2007-01-24 EP disclosed
WO-2006031891-A2 FAST-CURING MODIFIED SILOXANE COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2006-03-23 WO disclosed
US-20060058451-A1 Fast-curing modified siloxane compositions AMERON INTERNATIONAL, INC. 2006-03-16 US disclosed
WO-2005034205-A2 SELF ASSEMBLING NANOPARTICLE-POLYMER HYBRIDS DOW CORNING CORPORATION (US) 2005-04-14 WO disclosed
US-20020024011-A1 Method for correcting opaque defects in reticles for charged-particle-beam microlithography, and reticles produced using same NIKON CORPORATION 2002-02-28 US disclosed
US-3946131-A Glass fibers coated with silicon containing aminimide compounds OWENS-CORNING FIBERGLAS CORPORATION (US) 1976-03-23 US disclosed