Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5234739 | 0.87 | L3MBTL1 (0.38) | L3MBTL1LMNAHTTALDH1A1HDAC3 | |
| SCHEMBL5234665 | 0.86 | L3MBTL1 (0.37) | L3MBTL1LMNAHTTALDH1A1HDAC3 | |
| SCHEMBL5235798 | 0.86 | L3MBTL1 (0.37) | L3MBTL1LMNAHTTALDH1A1HDAC3 | |
| SCHEMBL5237267 | 0.85 | S1PR1 (0.38) | L3MBTL1LMNAHTTALDH1A1HDAC3 | |
| SCHEMBL5238798 | 0.85 | L3MBTL1 (0.36) | L3MBTL1LMNAHTTALDH1A1HDAC3 | |
| SCHEMBL5235215 | 0.81 | RAB9A (0.36) | L3MBTL1LMNAALDH1A1HDAC3HDAC1 | |
| SCHEMBL5231060 | 0.79 | L3MBTL1 (0.39) | L3MBTL1LMNAHTTALDH1A1HDAC3 | |
| SCHEMBL6624407 | 0.73 | — | — | |
| SCHEMBL5235699 | 0.70 | CYP2C9 (0.36) | L3MBTL1LMNACYP1A2CYP2C9TSHR | |
| SCHEMBL5230288 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1336612-B1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA (JP) | 2007-01-17 | — | — | EP | disclosed |
| US-6908913-B2 | Carbapenem derivatives | MEIJI SEIKI KAISHA, LTD. (JP) | 2005-06-21 | — | — | US | disclosed |
| US-20040038967-A1 | Novel carbapenem derivatives | MEIJI SEIKI KAISHA, LTD. (JP) | 2004-02-26 | — | — | US | disclosed |
| EP-1336612-A1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2003-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038967-A1 | Novel carbapenem derivatives | DHPS, HAMP, MCRS1 | L3MBTL1 2591/4885LMNA 894/4885HTT 2173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.