Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | S100A4 | P26447 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100131 | 0.83 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1HPGDRECQL | |
| SCHEMBL70062 | 0.83 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1HPGDRECQL | |
| SCHEMBL1080995 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TSHRS100A4TDP1GPR35 | |
| SCHEMBL29800736 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TSHRS100A4TDP1GPR35 | |
| SCHEMBL1167739 | 0.82 | TSHR (0.53) | ALDH1A1TSHRS100A4TDP1GPR35 | |
| SCHEMBL1232315 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TSHRS100A4TDP1GPR35 | |
| SCHEMBL30844575 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TSHRS100A4TDP1GPR35 | |
| SCHEMBL28408586 | 0.82 | S100A4 (0.46) | ALDH1A1TSHRS100A4TDP1HPGD | |
| SCHEMBL28408562 | 0.82 | S100A4 (0.46) | ALDH1A1TSHRS100A4TDP1GPR35 | |
| Iodide SCHEMBL9605320 | 0.82 | ALDH1A1 (0.62) | ALDH1A1TSHRTDP1HPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263735-B1 | ACID ADDITION SALTS OF IMIDAZOLIDINONES AS REACTION CATALYSTS | UNIV CALIFORNIA (US) | 2007-07-04 | — | — | EP | disclosed |
| EP-1002801-B1 | Chiral diphenyldiphosphines and d-8 metal complexes thereof | SOLVIAS AG (CH) | 2003-06-18 | — | — | EP | disclosed |
| US-6534434-B2 | Catalyst for unsaturated carbonyl compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-03-18 | — | — | US | disclosed |
| US-6515137-B2 | Enantioselectivity of alpha,beta-unsaturated aldehydes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-02-04 | — | — | US | disclosed |
| US-6369243-B1 | ACID CATALYST | THE REGENTS OF THE UNIVERISITY OF CALIFORNIA | 2002-04-09 | — | — | US | disclosed |
| US-20020016473-A1 | Catalytic processes employing chiral imidazolidinone-based catalyst composition | MACMILLAN DAVID W C (US) | 2002-02-07 | — | — | US | disclosed |
| US-20020013475-A1 | Chiral imidazolidinone-based catalyst composition and reaction system | MACMILLAN DAVID W C (US) | 2002-01-31 | — | — | US | disclosed |
| US-6307057-B1 | CATALYZE ENANTIOSELECTIVE REACTIONS, E.G., DIELS-ALDER REACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013475-A1 | Chiral imidazolidinone-based catalyst composition and reaction system | COASY, DHPS, INTS9 | ALDH1A1 78/4885TSHR 4061/4885S100A4 4431/4885 |
| US-20020016473-A1 | Catalytic processes employing chiral imidazolidinone-based catalyst composition | COASY, ALDH3A1, TALDO1 | ALDH1A1 40/4885TSHR 4574/4885S100A4 4208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.