Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5240712 | 0.84 | CYP1A2 (0.49) | CYP1A2LOXL2TGFBR1MAPK14RAB9A | |
| SCHEMBL5233929 | 0.82 | CYP1A2 (0.50) | CYP1A2LOXL2IDO1FLT1KDR | |
| SCHEMBL5233678 | 0.82 | RAB9A (0.56) | CYP1A2LOXL2IDO1FLT1KDR | |
| SCHEMBL4872056 | 0.81 | CYP1A2 (0.55) | CYP1A2LOXL2ALDH1A1KMT2A | |
| SCHEMBL4872415 | 0.78 | CYP1A2 (0.49) | CYP1A2LOXL2IDO1FLT1KDR | |
| SCHEMBL5238712 | 0.78 | CYP1A2 (0.51) | CYP1A2LOXL2KDRRAB9ANPC1 | |
| SCHEMBL5231886 | 0.78 | MGAM (0.53) | CYP1A2LOXL2ALDH1A1RAB9ANPC1 | |
| SCHEMBL5231990 | 0.78 | ALDH1A1 (0.56) | CYP1A2LOXL2ALDH1A1RAB9ANPC1 | |
| SCHEMBL5236574 | 0.77 | TSHR (0.48) | CYP1A2SMN1; SMN2KMT2A | |
| SCHEMBL29959459 | 0.76 | CYP1A2 (0.49) | CYP1A2LOXL2TGFBR1MAPK14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397364-B1 | NOVEL PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | LILLY CO ELI (US) | 2007-07-25 | — | — | EP | disclosed |