SCHEMBL5239001

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8233098	0.86	HTR2A (0.52)	HTR2AHTR2CHTR2BNPSR1MEN1
	SCHEMBL8234471	0.83	HTR2A (0.54)	HTR2AHTR2CHTR2BNPSR1MEN1
	SCHEMBL398693	0.81	HTR2A (0.51)	HTR2AHTR2CHTR2BNPSR1MEN1
	SCHEMBL1991168	0.80	HTR2A (0.50)	HTR2AHTR2CHTR2BNPSR1GLA
	SCHEMBL1992109	0.79	PKM (0.58)	HTR2AHTR2CHTR2BMEN1KMT2A
	SCHEMBL399849	0.79	HTR2A (0.50)	HTR2AHTR2CHTR2BMEN1KMT2A
	SCHEMBL20631047	0.77	HTR2A (0.62)	HTR2AHTR2CHTR2BMEN1KMT2A
	SCHEMBL5237835	0.73	HTR2A (1.00)	HTR2AHTR2CHTR2B
	SCHEMBL1852400	0.72	PKM (0.64)	HTR2AHTR2CHTR2BNPSR1MEN1
	SCHEMBL29992703	0.72	PKM (0.64)	HTR2AHTR2CHTR2BNPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.