Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5239013 | 0.73 | LOXL2 (0.47) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL3579185 | 0.68 | AR (0.43) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7854219 | 0.68 | ALDH1A1 (0.59) | MAPTSMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29502965 | 0.68 | MAPT (0.53) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL15688640 | 0.68 | RAB9A (0.46) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL18702691 | 0.68 | MAPT (0.53) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL3923636 | 0.67 | MAPT (0.66) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL11395546 | 0.67 | LOXL2 (0.52) | NPC1RAB9ALOXL2MAOACSF1R | |
| SCHEMBL27720646 | 0.66 | KCNA3 (0.56) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL13035481 | 0.66 | CCNB2 (0.46) | NPC1RAB9AMAPTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585740-A4 | PROCESS TO PREPARE PSOROSPERMIN | CYLENE PHARMACEUTICALS INC (US) | 2007-06-13 | — | — | EP | disclosed |
| EP-1585740-A2 | PROCESS TO PREPARE PSOROSPERMIN | Cylene Pharmaceuticals, Inc. (US) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004019888-A2 | PROCESS TO PREPARE PSOROSPERMIN | CYLENE PHARMACEUTICALS, INC. (US) | 2004-03-11 | — | — | WO | disclosed |