Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | BAX | Q07812 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1393658 | 0.92 | MAPT (0.52) | LTA4HEPHX2MAPTSLC6A2SLC6A4 | |
| SCHEMBL3306191 | 0.90 | LTA4H (0.57) | LTA4HEPHX2TSHRNR3C1MAPT | |
| SCHEMBL8113103 | 0.87 | GRIN2B (0.42) | LTA4HEPHX2TSHRMAPTKIF11 | |
| SCHEMBL220074 | 0.85 | MAPT (0.47) | EPHX2TSHRMAPTKIF11SMN1; SMN2 | |
| SCHEMBL7469958 | 0.83 | MAPT (0.45) | EPHX2TSHRMAPTKIF11SMN1; SMN2 | |
| SCHEMBL30056405 | 0.83 | MAPT (0.45) | EPHX2TSHRMAPTKIF11SMN1; SMN2 | |
| SCHEMBL18105336 | 0.83 | LTA4H (0.67) | LTA4HTSHRMAPTNR1H2BAX | |
| SCHEMBL314422 | 0.83 | LTA4H (0.67) | LTA4HTSHRMAPTNR1H2BAX | |
| SCHEMBL31360383 | 0.81 | CETP (0.43) | LTA4HEPHX2MAPTSLC6A2SLC6A4 | |
| Bromide SCHEMBL28835122 | 0.81 | MAPT (0.44) | EPHX2TSHRMAPTKIF11SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763515-A1 | 4-TRIFLUOROMETHOXYPHENOXYBENZOL-4'-SULFONIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF IN MEDICAMENTS | Sanofi-Aventis Deutschland GmbH (DE) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006002764-A1 | 4-TRIFLUOROMETHOXYPHENOXYBENZOL-4'-SULFONIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF IN MEDICAMENTS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-01-12 | — | — | WO | disclosed |