Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27555136 | 0.78 | CYP2D6 (0.33) | ADRA1AKDM4EHIF1ANAAA | |
| SCHEMBL11453750 | 0.76 | CYP2D6 (0.34) | ADRA1AKDM4EHIF1AEPHX2EPHX1 | |
| SCHEMBL19690668 | 0.75 | NAAA (0.35) | EPHX2EPHX1NAAA | |
| SCHEMBL933280 | 0.73 | KEAP1 (0.33) | KDM4EHIF1AEPHX2SMN1; SMN2 | |
| SCHEMBL27334904 | 0.71 | FFAR3 (0.31) | ADRA1ANAAASMN1; SMN2 | |
| SCHEMBL5271172 | 0.70 | SMN1; SMN2 (0.31) | EPHX2SMN1; SMN2 | |
| SCHEMBL5271175 | 0.70 | EPHX2 (0.33) | EPHX2EPHX1SSTR4SMN1; SMN2 | |
| SCHEMBL25429424 | 0.68 | KEAP1 (0.36) | EPHX1NAAASMN1; SMN2 | |
| SCHEMBL8392406 | 0.67 | KDM4E (0.50) | ADRA1AKDM4EMAPK1HIF1AEPHX1 | |
| SCHEMBL8392716 | 0.67 | KDM4E (0.50) | ADRA1AKDM4EMAPK1HIF1AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140203-B1 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2007-05-23 | — | — | EP | disclosed |