Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 6/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690863 | 0.85 | ADRA1A (0.57) | ADRA1DADRA1AADRA1B | |
| Bromide SCHEMBL7683252 | 0.84 | ADRA1A (0.56) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6193262 | 0.81 | ADRA1A (0.55) | ADRA1DADRA1AADRA1B | |
| SCHEMBL4538062 | 0.77 | ADRA1D (0.58) | ADRA1DADRA1AADRA1B | |
| SCHEMBL14621895 | 0.77 | DRD2 (0.67) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7301761 | 0.77 | ADRA1A (0.60) | ADRA1DADRA1AADRA1B | |
| SCHEMBL3954997 | 0.76 | ADRA1D (0.58) | ADRA1DADRA1AADRA1B | |
| SCHEMBL3955000 | 0.76 | ADRA1D (0.58) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL6194198 | 0.74 | ADRA1D (0.52) | ADRA1DADRA1AADRA1B | |
| SCHEMBL1050135 | 0.73 | DRD2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758583-A2 | ARYLPIPERAZINE DERIVATIVES USEFUL AS ADRENERGIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005118537-A2 | ARYLPIPERAZINE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-12-15 | — | — | WO | disclosed |