Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 7/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957751 | 0.86 | DRD2 (0.58) | ADRA1AADRA1DADRA1BHTR1A | |
| SCHEMBL7690863 | 0.85 | ADRA1A (0.57) | ADRA1AADRA1DADRA1BHTR1A | |
| Bromide SCHEMBL7683252 | 0.84 | ADRA1A (0.56) | ADRA1AADRA1DADRA1BHTR1A | |
| SCHEMBL5240356 | 0.81 | ADRA1D (0.52) | ADRA1AADRA1DADRA1B | |
| SCHEMBL14621895 | 0.77 | DRD2 (0.67) | ADRA1AADRA1DADRA1BHTR1A | |
| SCHEMBL5821266 | 0.77 | ADRA1A (0.49) | ADRA1AADRA1DADRA1BHTR1A | |
| SCHEMBL7301761 | 0.77 | ADRA1A (0.60) | ADRA1AADRA1DADRA1BHTR1A | |
| SCHEMBL5498735 | 0.76 | DRD2 (0.61) | ADRA1AADRA1DADRA1BHTR1A | |
| Ethylamine SCHEMBL7690866 | 0.76 | HTR6 (0.59) | ADRA1AADRA1DADRA1BHTR1A | |
| SCHEMBL30724862 | 0.76 | DRD2 (0.61) | ADRA1AADRA1DADRA1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1495000-A4 | ALPHA, OMEGA-DICARBOXIMIDE DERIVATIVES AS USEFUL URO-SELECTIVE A1A ADRENOCEPTOR BLOCKERS | RANBAXY LAB LTD (IN) | 2005-10-05 | — | — | EP | disclosed |
| EP-1495000-A1 | ALPHA, OMEGA-DICARBOXIMIDE DERIVATIVES AS USEFUL URO-SELECTIVE A1A ADRENOCEPTOR BLOCKERS | RANBAXY LABORATORIES, LTD. (IN) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003084928-A1 | ALPHA, OMEGA-DICARBOXIMIDE DERIVATIVES AS USEFUL URO-SELECTIVE Α1Α ADRENOCEPTOR BLOCKERS | RANBAXY LABORATORIES LIMITED (IN) | 2003-10-16 | — | — | WO | disclosed |