Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | CDK2 | P24941 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | MMP2 | P08253 | 2/20 | 0.61 |
| ▸ | EGFR | P00533 | 2/20 | 0.61 |
| ▸ | FYN | P06241 | 2/20 | 0.61 |
| ▸ | MMP9 | P14780 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
| ▸ | MMP12 | P39900 | 1/20 | 0.61 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.61 |
| ▸ | DBH | P09172 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122963 | 0.78 | ALDH1A1 (0.60) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| Pyrogallol SCHEMBL3532 | 0.77 | — | — | |
| Pyrogallol SCHEMBL170157 | 0.77 | ALDH1A1 (1.00) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| Pyrogallol SCHEMBL2063415 | 0.75 | ALDH1A1 (0.80) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| Pyrogallol SCHEMBL483095 | 0.75 | ALDH1A1 (0.80) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| Pyrogallol SCHEMBL25396043 | 0.74 | ALDH1A1 (0.67) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL524707 | 0.74 | DBH (1.00) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL193772 | 0.74 | CDK2 (1.00) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL24121632 | 0.74 | CDK2 (0.41) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL524689 | 0.74 | HPGD (0.64) | ALDH1A1HPGDALOX15HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107699532-B | 3, 7-dihydroxy tropolone high-yield strain and fermentation culture method thereof | 上海交通大学 | 2020-12-29 | — | — | CN | claimed |
| CN-107699581-B | 3, 7-dihydroxy tropolone biosynthesis gene cluster and application thereof | 上海交通大学 | 2020-12-29 | — | — | CN | claimed |
| US-20100152301-A1 | Treatment of Viral Infections | GOVERNMENT OF THE US, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-06-17 | — | — | US | claimed |
| EP-1976497-A2 | TREATMENT OF VIRAL INFECTIONS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-10-08 | — | — | EP | claimed |
| WO-2007065007-A9 | TREATMENT OF VIRAL INFECTIONS | US HEALTH (US) | 2007-09-13 | — | — | WO | claimed |
| WO-2007065007-A2 | TREATMENT OF VIRAL INFECTIONS | GOVERNMENT OF THE U.S.A., AS REPERSENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2007-06-07 | — | — | WO | claimed |
| US-4883758-A | Biologically pure culture of the microorganism Streptomycas tropolofaciens used for producing 3,7-dihydroxytropolone and antitumor use | BRISTOL-MYERS COMPANY (US) | 1989-11-28 | — | — | US | claimed |
| US-4833079-A | CULTURE OF STREPTOMYCES | BRISTOL-MYERS COMPANY (US) | 1989-05-23 | — | — | US | claimed |
| US-12357589-B2 | Inhibitors of Bunyaviridae and uses thereof | SAINT LOUIS UNIVERSITY (US) | 2025-07-15 | — | — | US | disclosed |
| US-20250009686-A1 | INHIBITORS OF BUNYAVIRIDAE AND USES THEREOF | SAINT LOUIS UNIVERSITY (US) | 2025-01-09 | — | — | US | disclosed |
| US-12121500-B2 | Inhibitors of Bunyaviridae and uses thereof | SAINT LOUIS UNIVERSITY (US) | 2024-10-22 | — | — | US | disclosed |
| US-20210393548-A1 | INHIBITORS OF BUNYAVIRIDAE AND USES THEREOF | SAINT LOUIS UNIVERSITY (US) | 2021-12-23 | — | — | US | disclosed |
| CN-107699581-B | 3, 7-dihydroxy tropolone biosynthesis gene cluster and application thereof | 上海交通大学 | 2020-12-29 | — | — | CN | disclosed |
| CN-107699532-B | 3, 7-dihydroxy tropolone high-yield strain and fermentation culture method thereof | 上海交通大学 | 2020-12-29 | — | — | CN | disclosed |
| US-4883758-A | Biologically pure culture of the microorganism Streptomycas tropolofaciens used for producing 3,7-dihydroxytropolone and antitumor use | BRISTOL-MYERS COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4883758-A | Biologically pure culture of the microorganism Streptomycas tropolofaciens used for producing 3,7-dihydroxytropolone and antitumor use | BRISTOL-MYERS COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4883758-A | Biologically pure culture of the microorganism Streptomycas tropolofaciens used for producing 3,7-dihydroxytropolone and antitumor use | BRISTOL-MYERS COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4833079-A | CULTURE OF STREPTOMYCES | BRISTOL-MYERS COMPANY (US) | 1989-05-23 | — | — | US | disclosed |
| US-4833079-A | CULTURE OF STREPTOMYCES | BRISTOL-MYERS COMPANY (US) | 1989-05-23 | — | — | US | disclosed |
| US-4833079-A | CULTURE OF STREPTOMYCES | BRISTOL-MYERS COMPANY (US) | 1989-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210393548-A1 | INHIBITORS OF BUNYAVIRIDAE AND USES THEREOF | HAVCR2, REN, CTSE | ALDH1A1 1612/4885HPGD 3129/4885ALOX15 4624/4885 |
| US-20250009686-A1 | INHIBITORS OF BUNYAVIRIDAE AND USES THEREOF | HAVCR2, REN, CTSE | ALDH1A1 1612/4885HPGD 3129/4885ALOX15 4624/4885 |
| US-12121500-B2 | Inhibitors of Bunyaviridae and uses thereof | HAVCR2, REN, CTSE | ALDH1A1 1503/4885HPGD 2902/4885ALOX15 4568/4885 |
| US-12357589-B2 | Inhibitors of Bunyaviridae and uses thereof | HAVCR2, REN, CTSE | ALDH1A1 1503/4885HPGD 2902/4885ALOX15 4568/4885 |
| US-20100152301-A1 | Treatment of Viral Infections | CD4, TYMP, DUT | ALDH1A1 1004/4885HPGD 1380/4885ALOX15 4261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.