SCHEMBL524173

SCHEMBL524173

N#Cc1ccc(O)c(C(F)(F)F)c1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
P4HB P07237 2/20 0.56
TRPV4 Q9HBA0 1/20 0.54
CYP19A1 P11511 2/20 0.50
KIF11 P52732 2/20 0.49
TMPRSS4 Q9NRS4 1/20 0.48
AR P10275 8/20 0.44
CA12 O43570 1/20 0.43
CA2 P00918 1/20 0.43
CA3 P07451 1/20 0.43
CA6 P23280 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
PGR P06401 1/20 0.42
MRGPRX4 Q96LA9 1/20 0.42
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
PDK2 Q15119 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7275576 0.87 KIF11 (0.63) P4HBTRPV4CYP19A1KIF11AR
SCHEMBL8255777 0.86 KIF11 (0.51) P4HBTRPV4CYP19A1KIF11TMPRSS4
SCHEMBL30669214 0.86 KIF11 (0.51) P4HBTRPV4CYP19A1KIF11TMPRSS4
SCHEMBL7569957 0.83 TRPV4 (0.58) P4HBTRPV4KIF11TMPRSS4AR
SCHEMBL7604551 0.81 TRPV4 (0.56) P4HBTRPV4KIF11TMPRSS4AR
SCHEMBL185191 0.79 KIF11 (0.58) P4HBTRPV4KIF11TMPRSS4AR
SCHEMBL29437966 0.79 ALDH1A1 (0.57) P4HBTRPV4KIF11CA12CA2
SCHEMBL29421437 0.79 KIF11 (0.58) P4HBTRPV4KIF11TMPRSS4AR
SCHEMBL1003776 0.79 AR (0.58) TRPV4ARPGR
SCHEMBL5368308 0.79 ALDH1A1 (0.57) P4HBTRPV4KIF11CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617762-B2 Carboxy derivatives with antiinflamatory properties SITRYX THERAPEUTICS LIMITED (GB) 2026-05-05 US disclosed
EP-4081511-B3 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES SITRYX THERAPEUTICS LTD (GB) 2026-03-04 EP disclosed
CN-120040369-A Oxadiazole amide c-Myc inhibitor and preparation method and application thereof 上海深势唯思科技有限责任公司 2025-05-27 CN disclosed
US-20250049772-A1 PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-02-13 US disclosed
CN-119409594-A Synthesis and refining method of important intermediate of monetel 江苏天和制药股份有限公司 2025-02-11 CN disclosed
EP-4085048-B1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-11-13 EP disclosed
EP-4442319-A2 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES Sitryx Therapeutics Limited (GB) 2024-10-09 EP disclosed
EP-3904329-B1 PROCESS FOR HYDRODEFLUORINATION OF AROMATIC TRIFLUOROMETHYL DERIVATIVES UNIV PARDUBICE (CZ) 2024-09-04 EP disclosed
CN-114901635-B Herbicidal compounds 先正达农作物保护股份公司 2024-08-16 CN disclosed
EP-4081511-B1 CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES SITRYX THERAPEUTICS LTD (GB) 2024-07-31 EP disclosed
US-5464848-A 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents STERLING WINTHROP INC. (US) 1995-11-07 US disclosed
US-5349068-A 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents STERLING WINTHROP INC. (US) 1994-09-20 US disclosed
EP-0566199-A1 1,2,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use a s antiviral agents STERLING WINTHROP INC. (US) 1993-10-20 EP disclosed
EP-0523803-A1 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents STERLING WINTHROP INC. (US) 1993-01-20 EP disclosed
US-5175177-A 1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS STERLING DRUG INC. (US) 1992-12-29 US disclosed
EP-0207454-B1 ISOXAZOLE AND FURAN DERIVATIVES, THEIR PREPARATION AND USE AS ANTIVIRAL AGENTS STERLING WINTHROP INC. (US) 1992-09-09 EP disclosed
US-5002960-A Viricides for combating picornaviruses STERLING DRUG, INC. (US) 1991-03-26 US disclosed
US-4939267-A Viricides STERLING DRUG INC. (US) 1990-07-03 US disclosed
US-4843087-A OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES STERLING DRUG INC. (US) 1989-06-27 US disclosed
EP-0207454-A2 Isoxazole and furan derivatives, their preparation and use as antiviral agents STERLING WINTHROP INC. (US) 1987-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250049772-A1 PIPERIDINYL-3-(ARYLOXY)PROPANAMIDES AND PROPANOATES SSTR4, SSTR3, NPY4R P4HB 1578/4885TRPV4 1250/4885CYP19A1 688/4885
US-12617762-B2 Carboxy derivatives with antiinflamatory properties CCR1, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 P4HB 1848/4885TRPV4 4186/4885CYP19A1 4120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.