Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 14/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.40 |
| ▸ | GABRP | O00591 | 11/20 | 0.40 |
| ▸ | GABRD | O14764 | 11/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 11/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 11/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 11/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 11/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 11/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 11/20 | 0.40 |
| ▸ | GABRE | P78334 | 11/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 11/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 11/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 11/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 11/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3191209 | 1.00 | LMNA (0.42) | LMNAKMT2AGABRB3GABRA2GABRB2 | |
| SCHEMBL9218268 | 0.92 | GABRB3 (0.42) | LMNAKMT2AGABRB3GABRA2GABRB2 | |
| SCHEMBL9218260 | 0.92 | GABRB3 (0.42) | LMNAKMT2AGABRB3GABRA2GABRB2 | |
| SCHEMBL9216331 | 0.91 | GABRP (0.46) | LMNAGABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9504165 | 0.89 | GABRB3 (0.38) | LMNAKMT2AGABRB3GABRA2GABRB2 | |
| SCHEMBL9504169 | 0.89 | GABRB3 (0.38) | LMNAKMT2AGABRB3GABRA2GABRB2 | |
| SCHEMBL9502977 | 0.88 | GABRA2 (0.39) | LMNAGABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9502983 | 0.88 | GABRA2 (0.39) | LMNAGABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9704872 | 0.84 | GABRP (0.44) | LMNAGABRB3GABRA2GABRB2GABRP | |
| SCHEMBL9704876 | 0.84 | GABRP (0.44) | LMNAGABRB3GABRA2GABRB2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1618104-B1 | METHOD FOR SYNTHESISING 5-CHLORO-1-ARYL-4-(4, 5-DICYANO-1H-IMIDAZOL-2-YL)-3-ALKYL-1H-PYRAZOLE DERIVATIVES | EVULTIS (CH) | 2007-06-20 | — | — | EP | disclosed |