Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | DDT | P30046 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5247572 | 0.92 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2NAMPT | |
| SCHEMBL5244312 | 0.92 | SMPD1 (0.35) | TAS1R3TAS1R1TAS1R2NAMPTPTGER4 | |
| SCHEMBL3102931 | 0.88 | TP53 (0.39) | — | |
| SCHEMBL5244618 | 0.87 | TAS1R3 (0.33) | TAS1R3TAS1R1TAS1R2NAMPTPTGER4 | |
| SCHEMBL3104911 | 0.85 | S1PR1 (0.41) | NOTUMLOXL2 | |
| SCHEMBL5244782 | 0.84 | SMPD1 (0.36) | TAS1R3TAS1R1TAS1R2NAMPT | |
| SCHEMBL5246728 | 0.83 | GLS (0.34) | PTGER4DDT | |
| SCHEMBL5246041 | 0.82 | MIF (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL3109192 | 0.82 | ACKR3 (0.40) | — | |
| SCHEMBL5248109 | 0.82 | EGLN1 (0.38) | NAMPTPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |