Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | DDT | P30046 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248464 | 0.92 | BRD4 (0.35) | GLSL3MBTL1MIFPDE4APDE4B | |
| SCHEMBL5244109 | 0.86 | MIF (0.47) | MIFALDH1A1GAAKMT2AMAPT | |
| SCHEMBL5244507 | 0.85 | BRD4 (0.40) | MIFALDH1A1GAAPOLBMAPT | |
| SCHEMBL3102931 | 0.83 | TP53 (0.39) | MAPTHPGD | |
| SCHEMBL5246004 | 0.83 | TAS1R3 (0.34) | PTGER4DDT | |
| SCHEMBL3104911 | 0.83 | S1PR1 (0.41) | — | |
| SCHEMBL5244591 | 0.82 | DDT (0.34) | GLSMIFDDT | |
| SCHEMBL5245155 | 0.81 | KDM4E (0.44) | MIFALDH1A1POLBMAPT | |
| SCHEMBL5246041 | 0.81 | MIF (0.45) | GLSMIFPDE4APDE4BPDE4C | |
| SCHEMBL5244708 | 0.80 | DDT (0.35) | GLSMIFDDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |