Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112834 | 0.89 | HPGD (0.43) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL3117772 | 0.88 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL5245992 | 0.85 | SMN1; SMN2 (0.52) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL3113746 | 0.84 | RIPK1 (0.41) | RAB9ANPC1SMN1; SMN2NAMPTHPGD | |
| SCHEMBL3112551 | 0.84 | XDH (0.45) | RAB9ANPC1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL5247650 | 0.84 | RAB9A (0.43) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL3114145 | 0.84 | CYP1A2 (0.42) | RAB9ANPC1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL3114784 | 0.84 | RIPK1 (0.39) | RAB9AHPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL5244694 | 0.83 | HPGD (0.48) | RAB9ASMN1; SMN2HPGDMAPK1ALDH1A1 | |
| SCHEMBL5249116 | 0.82 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2NAMPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |