Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 11/20 | 0.41 |
| ▸ | DDT | P30046 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246995 | 0.94 | DDT (0.41) | EPHX2DDTMIF | |
| SCHEMBL5247966 | 0.92 | EPHX2 (0.43) | EPHX2NR1H4MEN1KMT2ANPC1 | |
| SCHEMBL5246077 | 0.92 | MMP13 (0.37) | EPHX2DDTHDAC8MIF | |
| SCHEMBL5246041 | 0.91 | MIF (0.45) | EPHX2DDTMIF | |
| SCHEMBL5244132 | 0.89 | HTR2C (0.43) | EPHX2NR1H4CYP1A2CYP2C19 | |
| SCHEMBL5246799 | 0.89 | PSEN1 (0.41) | DDTCYP1A2CYP2C19MIF | |
| SCHEMBL5248109 | 0.89 | EGLN1 (0.38) | EPHX2DDTHDAC8MIF | |
| SCHEMBL5247824 | 0.89 | MMP13 (0.39) | EPHX2DDTMIF | |
| SCHEMBL5245570 | 0.88 | LMNA (0.42) | EPHX2DDTHDAC8HDAC6 | |
| SCHEMBL5247395 | 0.88 | DDT (0.43) | EPHX2DDTMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |