Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDT | P30046 | 3/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245221 | 0.94 | HPGD (0.44) | DDTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5247966 | 0.94 | EPHX2 (0.43) | DRD2EPHX2MIF | |
| SCHEMBL5246995 | 0.92 | DDT (0.41) | DDTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5244424 | 0.92 | DDT (0.52) | DDTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5244462 | 0.91 | MAPT (0.40) | DRD2MIFMMP13 | |
| SCHEMBL5244376 | 0.91 | PSEN1 (0.41) | DDTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5249096 | 0.91 | ALDH1A1 (0.46) | PPARGPPARAEPHX2GLSKDM4E | |
| SCHEMBL5246767 | 0.90 | MIF (0.47) | DDTPSEN1PSEN2APH1BNCSTN | |
| Trifluoroacetic Acid SCHEMBL5246592 | 0.90 | BRD4 (0.41) | DDTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5248742 | 0.89 | DDT (0.39) | DDTPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |