Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDT | P30046 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5249242 | 0.93 | DDT (0.37) | DDTPPARDPPARAPPARGPSEN1 | |
| SCHEMBL5245935 | 0.92 | ROCK2 (0.41) | DDTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5247395 | 0.89 | DDT (0.43) | DDTPPARDPPARAPPARGPSEN1 | |
| SCHEMBL5244462 | 0.89 | MAPT (0.40) | BRD4MMP13MIF | |
| SCHEMBL5247751 | 0.88 | EPHX2 (0.36) | DDTPPARDPPARAPPARGPSEN1 | |
| SCHEMBL5244638 | 0.88 | LMNA (0.39) | DDTROCK2ROCK1BRD4MMP13 | |
| SCHEMBL5245221 | 0.88 | HPGD (0.44) | DDTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5244706 | 0.88 | ROCK2 (0.40) | DDTPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5244424 | 0.87 | DDT (0.52) | DDTPPARGPSEN1PSEN2APH1B | |
| SCHEMBL5244376 | 0.87 | PSEN1 (0.41) | DDTPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |