Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | DDT | P30046 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5244462 | 0.93 | MAPT (0.40) | MIFBRD4SMN1; SMN2GAA | |
| SCHEMBL5246709 | 0.92 | ROCK2 (0.42) | MIFBRD4LMNAPSEN1PSEN2 | |
| SCHEMBL5244706 | 0.92 | ROCK2 (0.40) | MIFBRD4PSEN1PSEN2APH1B | |
| SCHEMBL5246245 | 0.91 | ROCK2 (0.41) | MIFBRD4PSEN1PSEN2APH1B | |
| SCHEMBL5246030 | 0.91 | LMNA (0.42) | MIFBRD4ALDH1A1LMNAPSEN1 | |
| SCHEMBL5244747 | 0.91 | BRD4 (0.47) | BRD4LMNAPSEN1PSEN2APH1B | |
| SCHEMBL5248346 | 0.91 | ROCK2 (0.45) | MIFBRD4LMNAPSEN1PSEN2 | |
| SCHEMBL5244330 | 0.90 | BRD4 (0.42) | MIFBRD4PSEN1PSEN2APH1B | |
| SCHEMBL5247395 | 0.90 | DDT (0.43) | MIFALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL5247966 | 0.90 | EPHX2 (0.43) | MIFLMNAMEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |