Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5248059 | 0.92 | LMNA (0.46) | RAB9ANPC1HTTKMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL5248300 | 0.88 | NPC1 (0.38) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL5247650 | 0.83 | RAB9A (0.43) | GAARAB9ASMN1; SMN2NPC1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5247370 | 0.81 | LMNA (0.48) | GAASMN1; SMN2HTTNAMPTKMT2A | |
| SCHEMBL3112834 | 0.81 | HPGD (0.43) | RAB9ASMN1; SMN2NPC1ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL5247363 | 0.80 | LMNA (0.47) | GAASMN1; SMN2HTTNAMPTTSHR | |
| SCHEMBL5244694 | 0.80 | HPGD (0.48) | RAB9ASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL5245992 | 0.79 | SMN1; SMN2 (0.52) | RAB9ASMN1; SMN2NPC1HTTKMT2A | |
| SCHEMBL5248728 | 0.79 | ABCB1 (0.47) | GAARAB9ASMN1; SMN2NPC1NAMPT | |
| SCHEMBL5249116 | 0.79 | NPC1 (0.50) | GAARAB9ASMN1; SMN2NPC1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |