Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5247370 | 0.90 | LMNA (0.48) | LMNAMAPK1ALDH1A1HTTMAPT | |
| SCHEMBL5244694 | 0.87 | HPGD (0.48) | LMNAMAPK1ALDH1A1HTTMAPT | |
| Trifluoroacetic Acid SCHEMBL5248059 | 0.85 | LMNA (0.46) | LMNAALDH1A1HTTPOLBHPGD | |
| SCHEMBL5246999 | 0.84 | HDAC1 (0.46) | LMNAALDH1A1MAPT | |
| SCHEMBL5244318 | 0.83 | CCR1 (0.59) | GAAMEN1KMT2ATDP1 | |
| SCHEMBL5244366 | 0.82 | CCR1 (0.45) | LMNAALDH1A1MAPTGAAMEN1 | |
| SCHEMBL5246379 | 0.82 | MLYCD (0.50) | LMNAALDH1A1GAAHPGDNPSR1 | |
| SCHEMBL5244456 | 0.82 | LMNA (0.57) | LMNAALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL5244148 | 0.81 | MAPK14 (0.52) | SMN1; SMN2NAMPTL3MBTL1ABCB1 | |
| SCHEMBL5249308 | 0.81 | RIPK1 (0.46) | LMNAALDH1A1MAPTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |