Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248904 | 0.91 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTLMNAALDH1A1HTT | |
| SCHEMBL5246041 | 0.89 | MIF (0.45) | LMNAALDH1A1DRD2DRD3MIF | |
| SCHEMBL5245310 | 0.87 | DRD2 (0.38) | DRD2DRD3MIFDGAT1 | |
| SCHEMBL3104911 | 0.87 | S1PR1 (0.41) | DRD2DRD3DGAT1 | |
| SCHEMBL3102931 | 0.85 | TP53 (0.39) | SMN1; SMN2MAPTLMNAHTTDRD2 | |
| SCHEMBL5244596 | 0.85 | DRD2 (0.36) | DRD2DRD3MEN1NPC1KMT2A | |
| SCHEMBL5248217 | 0.85 | NAMPT (0.38) | SMN1; SMN2MAPTLMNAKCNH2SCN9A | |
| Trifluoroacetic Acid SCHEMBL5245953 | 0.84 | MAPT (0.30) | SMN1; SMN2MAPT | |
| SCHEMBL3111267 | 0.83 | GLS (0.43) | MIF | |
| Trifluoroacetic Acid SCHEMBL5246340 | 0.83 | NPC1 (0.38) | SMN1; SMN2ALDH1A1HTTDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |