Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250335 | 0.91 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL5246767 | 0.88 | MIF (0.47) | SMN1; SMN2BRD4LMNAALDH1A1HTT | |
| SCHEMBL5246426 | 0.87 | BRD4 (0.41) | BRD4DRD2DRD3MIF | |
| SCHEMBL5244426 | 0.85 | DRD2 (0.37) | BRD4DRD2DRD3NPC1MEN1 | |
| SCHEMBL5248092 | 0.84 | MAPT (0.32) | SMN1; SMN2MAPTBRD4DRD2DRD3 | |
| SCHEMBL5246401 | 0.84 | BRD4 (0.41) | SMN1; SMN2MAPTBRD4LMNANPC1 | |
| SCHEMBL3107524 | 0.84 | BRD4 (0.49) | SMN1; SMN2MAPTBRD4ALDH1A1KDM4E | |
| SCHEMBL5247137 | 0.83 | SMPD1 (0.40) | SMN1; SMN2MAPTBRD4 | |
| SCHEMBL5246709 | 0.82 | ROCK2 (0.42) | MAPTBRD4LMNAGAAMIF | |
| SCHEMBL5248515 | 0.82 | DDT (0.39) | BRD4DRD2MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867331-A1 | TRIAZOLE DERIVATIVE AND THE USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-12-19 | — | — | EP | disclosed |